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The Best AI PDF Annotation Tools (and What They Do)

A guide to AI PDF annotation tools — AI-assisted markup versus reading layers that highlight and explain passages, and which one fits how you actually read.

Lewis Hadden3 min read

"AI PDF annotation" gets searched by two groups of people who want opposite things. One wants AI help marking up a PDF — highlighting, commenting, and saving those annotations to the file. The other wants AI to help them understand a PDF — explaining dense passages and pointing to the parts that matter. Most roundups blur the two. This guide separates them, so you pick a tool that does the thing you actually need.

Two very different meanings of "annotate"

  • AI-assisted markup — tools that let you (or an AI) highlight, comment on, and mark up a PDF, then save those annotations back into the document to share or keep. This is the classic PDF-annotation workflow, now with AI features layered on.
  • AI reading layers — tools that highlight and explain passages as you read to help you understand the document, without necessarily saving markup into the file. The "annotation" here is about comprehension, not producing a marked-up copy.

Neither is better in the abstract. If your goal is a shareable, annotated PDF, you want the first. If your goal is to get through a hard document and trust what you took from it, you want the second.

AI-assisted markup tools

If you need saved highlights and comments in the file itself — for review workflows, sign-off, or collaboration — look at dedicated PDF editors with AI features. Adobe Acrobat, Foxit, and similar editors let you mark up PDFs and increasingly bundle AI summarisation and Q&A alongside the markup tools. They're the right pick when the output is an annotated document.

The trade-off is that they're editing suites first — often subscription-based, PDF-centric, and heavier than you need if you only want to read and understand. (On Acrobat's AI specifically, see our Adobe Acrobat AI Assistant review.)

AI reading layers — highlight, explain, and verify

If your real goal is understanding, a reading layer is the better fit. Sidenote sits in this camp. It's a browser reading assistant, not a markup editor — and it's worth being precise about what that means: it doesn't save highlights and comments back into your PDF. What it does is help you read and trust the document.

  • Highlight to explain. Select any passage and get a plain-language explanation grounded in that passage and its surrounding context, with depth levels for how simply you want it put.
  • Every answer is cited. Ask a question and each claim carries a scroll-to-source citation: click it and the PDF scrolls to the exact sentence and highlights it in place.
  • Nothing invented. Claims that can't be matched to a real passage are dropped server-side, so the explanations and answers you get are anchored to what the document actually says.
  • Works beyond PDFs. The same highlight-and-explain reading layer works on scanned PDFs (via OCR), web pages, Confluence, Notion, Google Docs and more.

So Sidenote's "annotation" is the reading kind: it highlights sources and explains passages to help you understand, rather than producing a marked-up file to send on.

Which type of tool do you need?

You want to…Reach forExample
Save highlights/comments into the fileAn AI-enabled PDF editorAcrobat, Foxit
Understand a dense passage as you readAn AI reading layerSidenote (Explain)
Get cited answers you can verifyA citation-first readerSidenote (Citations)
Mark up and share for reviewA PDF editor with collaborationAcrobat, Foxit
Frequently asked questions
If you need saved markup in the file, use an AI-enabled PDF editor such as Acrobat or Foxit — those produce annotations you can share. If you want highlighting that helps you read — jumping to and highlighting the exact source of an answer — a reading layer like Sidenote does that in place, without saving markup back to the document.
Not in the markup sense — it doesn't save highlights or comments into your file. It's a reading and citation layer: it highlights the exact source passage behind any answer and lets you highlight a passage to get a cited, plain-language explanation. If you need a marked-up file to hand off, use a PDF editor instead.
For comprehension rather than markup, a citation-first reading layer works best, because you can check every explanation against the source. Sidenote explains highlighted passages and answers questions with click-to-source citations, and drops claims it can't ground in the text.
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